Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.38 |
| ▸ | PGR | P06401 | 6/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.32 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754520 | 0.84 | BRD4 (0.35) | ARPGRBRD4SLC22A12PSIP1 | |
| SCHEMBL7753846 | 0.82 | BRD4 (0.35) | ARPGRBRD4SLC22A12 | |
| SCHEMBL6308458 | 0.81 | PGR (0.40) | ARPGRBRD4 | |
| SCHEMBL7157679 | 0.80 | PGR (0.39) | ARPGRBRD4 | |
| Potassium SCHEMBL7157685 | 0.80 | PGR (0.39) | ARPGRBRD4 | |
| SCHEMBL6307788 | 0.79 | CTSK (0.36) | ARPGRBRD4 | |
| SCHEMBL7941767 | 0.78 | PGR (0.36) | ARPGRBRD4SLC22A12PSIP1 | |
| SCHEMBL8505383 | 0.76 | PGR (0.37) | ARPGRBRD4SLC22A12PSIP1 | |
| SCHEMBL6174842 | 0.76 | PGR (0.41) | ARPGRBRD4SLC22A12PSIP1 | |
| SCHEMBL7695435 | 0.75 | PGR (0.40) | ARPGRBRD4SLC22A12BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |