Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8757566 | 0.91 | PDPK1 (0.40) | ALDH1A1KDM4ECA2CYP3A4HDAC3 | |
| SCHEMBL8757678 | 0.90 | PDPK1 (0.42) | ALDH1A1KDM4ECA2CYP3A4HDAC3 | |
| SCHEMBL9109873 | 0.88 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1SOAT2ACAT1SOAT1 | |
| SCHEMBL9109323 | 0.88 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1SOAT2ACAT1SOAT1 | |
| SCHEMBL8757544 | 0.87 | PRSS1 (0.47) | ALDH1A1KDM4EPRSS1PRSS2PRSS3 | |
| SCHEMBL8757717 | 0.87 | PDPK1 (0.40) | ALDH1A1KDM4EPRSS1PRSS2PRSS3 | |
| SCHEMBL8757719 | 0.86 | MMP2 (0.43) | PRSS1PRSS2PRSS3PDPK1CYSLTR2 | |
| SCHEMBL7756671 | 0.83 | CYP2C9 (0.40) | KDM4EPRSS1PRSS2PRSS3CYSLTR2 | |
| SCHEMBL8757660 | 0.81 | MMP2 (0.45) | ALDH1A1PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL8757582 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764636-B1 | Thiopropionate synergists | GOODYEAR TIRE & RUBBER (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-0764636-A2 | Thiopropionate synergists | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |