Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 18/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645755 | 0.88 | PLA2G2A (0.54) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL7192247 | 0.86 | PLA2G1B (0.57) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL14394327 | 0.84 | PLA2G1B (0.43) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL14394234 | 0.82 | PLA2G1B (0.58) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL13893641 | 0.80 | PLA2G1B (0.51) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL7946056 | 0.78 | PLA2G2A (0.46) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL14394323 | 0.78 | PLA2G1B (0.48) | PLA2G1BPLA2G2A | |
| SCHEMBL7193741 | 0.78 | PLA2G1B (0.65) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL13893693 | 0.78 | PLA2G1B (0.67) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL13888714 | 0.77 | PLA2G1B (0.42) | PLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066111-A1 | COMPOSITIONS CONTAINING POTENTIAL SPLA2 INHIBITORS FOR THE TREATMENT OF PAIN | ELI LILLY AND COMPANY (US) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001055108-A2 | USE OF SPL A2 INHIBITORS FOR THE TREATMENT OF INFLAMMATION | ELI LILLY AND COMPANY (US) | 2001-08-02 | — | — | WO | disclosed |