Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 17/20 | 0.45 |
| ▸ | PLA2G2E | Q9NZK7 | 2/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.45 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192818 | 0.88 | PLA2G1B (0.55) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G2F | |
| SCHEMBL7645755 | 0.87 | PLA2G2A (0.54) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G2F | |
| SCHEMBL7736651 | 0.86 | PLA2G2A (0.47) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G2F | |
| SCHEMBL7736657 | 0.85 | PLA2G2A (0.47) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G2F | |
| SCHEMBL7753525 | 0.84 | PLA2G2A (0.49) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G2F | |
| SCHEMBL7193717 | 0.79 | PLA2G1B (0.58) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G2F | |
| SCHEMBL7754878 | 0.78 | PLA2G1B (0.45) | PLA2G2APLA2G1BPLA2G2EPLA2G5 | |
| SCHEMBL7196785 | 0.78 | PLA2G1B (0.67) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G2F | |
| SCHEMBL13888601 | 0.78 | PLA2G1B (0.55) | PLA2G2APLA2G1BPLA2G2EPLA2G5PLA2G2F | |
| SCHEMBL14394230 | 0.77 | PLA2G1B (0.58) | PLA2G2APLA2G1BPLA2G2EPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066111-A1 | COMPOSITIONS CONTAINING POTENTIAL SPLA2 INHIBITORS FOR THE TREATMENT OF PAIN | ELI LILLY AND COMPANY (US) | 2001-09-13 | — | — | WO | disclosed |