Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30683811 | 0.88 | NPC1 (0.58) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL1703200 | 0.84 | LMNA (0.63) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL13412684 | 0.80 | NPC1 (0.77) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL9284695 | 0.78 | NPC1 (0.60) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL8088622 | 0.74 | NPC1 (0.62) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL9189241 | 0.74 | KMT2A (0.44) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL9188428 | 0.74 | NPC1 (0.50) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL1702661 | 0.72 | LMNA (0.49) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL18928204 | 0.72 | KDM4E (0.44) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL7857203 | 0.72 | NPC1 (0.69) | NPC1RAB9ALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001019681-A | SULFONATED BENZOTRIAZOLE-BASED COMPOUND | OSAKA SEIKA KOGYO KK | 2001-01-23 | — | — | JP | disclosed |