SCHEMBL1703200

SCHEMBL1703200

Oc1ccc(-c2ccccc2)cc1-n1nc2ccccc2n1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.63
NPC1 O15118 2/20 0.63
RAB9A P51151 2/20 0.63
ALOX5 P09917 1/20 0.50
KDM4E B2RXH2 4/20 0.46
HPGD P15428 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
USP2 O75604 1/20 0.46
HSP90AA1 P07900 1/20 0.46
GAA P10253 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
HTT P42858 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ESR2 Q92731 1/20 0.46
ACMSD Q8TDX5 3/20 0.43
HNF4A P41235 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13412684 0.89 NPC1 (0.77) LMNANPC1RAB9AALOX5KDM4E
SCHEMBL1702661 0.87 LMNA (0.49) LMNANPC1RAB9AALOX5KDM4E
SCHEMBL9408847 0.84 NPC1 (0.47) LMNANPC1RAB9AALOX5KDM4E
SCHEMBL28375372 0.84 NPC1 (0.73) LMNANPC1RAB9AALOX5KDM4E
SCHEMBL28375928 0.84 NPC1 (0.73) LMNANPC1RAB9AALOX5KDM4E
SCHEMBL7754889 0.84 NPC1 (0.52) LMNANPC1RAB9AALOX5KDM4E
SCHEMBL11595373 0.83 NPC1 (0.49) LMNANPC1RAB9AKDM4EHPGD
SCHEMBL30337840 0.80 NPC1 (0.69) LMNANPC1RAB9AKDM4EHPGD
SCHEMBL7857203 0.80 NPC1 (0.69) LMNANPC1RAB9AKDM4EHPGD
SCHEMBL31711445 0.80 RAB9A (0.63) LMNANPC1RAB9AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2063295-B1 Fluorescent retroreflective sheeting NIPPON CARBIDE KOGYO KK (JP) 2012-04-18 EP disclosed
US-20100276073-A1 Surface Substrate Film for Motor Vehicle Brade Disc Antirust Film LINTEC CORPORATION 2010-11-04 US disclosed
EP-1748382-B1 Integrated circuit enclosed retroreflective product NIPPON CARBIDE KOGYO KK (JP) 2010-07-07 EP disclosed
EP-1052223-B1 HYDROTALCITE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL FILM CONTAINING THE SAME KYOWA CHEM IND CO LTD (JP) 2010-06-16 EP disclosed
EP-1903481-B1 Integrated circuit enclosed retroreflective product NIPPON CARBIDE KOGYO KK (JP) 2009-10-28 EP disclosed
EP-1741743-B1 SURFACE SUBSTRATE FILM FOR AUTOMOBILE BRAKE DISC ANTI-RUST FILM LINTEC CORP (JP) 2009-10-07 EP disclosed
US-7598874-B2 Integrated-circuit enclosed retroreflective product NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 2009-10-06 US disclosed
EP-2063295-A1 Fluorescent retroreflective sheeting Nippon Carbide Kogyo Kabushiki Kaisha (JP) 2009-05-27 EP disclosed
WO-2008131921-A1 SILYLATED, SUBSTITUTED BENZOTRIAZOLYLPHENOL COMPOUNDS ISDIN S.A. (ES) 2008-11-06 WO disclosed
WO-2008131921-A1 SILYLATED, SUBSTITUTED BENZOTRIAZOLYLPHENOL COMPOUNDS ISDIN S.A. (ES) 2008-11-06 WO disclosed
EP-0134389-A2 Vinyl chloride resin composition NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1985-03-20 EP disclosed
US-4467035-A Cultivation of phototrophic bacteria in the absence of ultraviolet light NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1984-08-21 US disclosed
EP-0065574-A1 PHOTOSYNTHETIC BACTERIA CULTURE NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1982-12-01 EP disclosed
EP-0031302-A2 Benzotriazole UV absorbers, process for their preparation and stabilized mixtures CIBA-GEIGY AG (CH) 1981-07-01 EP disclosed
US-4235043-A Method for cultivating algae and a covering material used therefor Nippon Carbide Kogyo Kabashiki Kaisha (JP) 1980-11-25 US disclosed
US-4128559-A ANTIDEPRESSANT EASTMAN KODAK COMPANY (US) 1978-12-05 US disclosed
US-4041011-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1977-08-09 US disclosed
US-3936418-A Benzotriazole ortho-ester ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed
US-3935164-A NICKEL 3,5-DI-TERT-ALKYL 4-HYDROXYBENZOATE, AND A BENZOPHENONE OR BENZOTRIAZOLE CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed
US-3935163-A NICKEL BIS(3,5-DI-TERT-ALKYL-4-HYDROXY BENZOATE AND A BENZOPHENONE OR BENZOTRIAZOLE CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed