Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5839487 | 0.86 | TSHR (0.52) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL17167809 | 0.81 | MMP2 (0.33) | TSHRKMT2AMEN1 | |
| SCHEMBL12157779 | 0.80 | — | — | |
| SCHEMBL14969719 | 0.79 | TSHR (0.50) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL20429066 | 0.79 | TSHR (0.44) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL1344130 | 0.78 | ALDH1A1 (0.37) | TSHRALDH1A1 | |
| SCHEMBL17167156 | 0.78 | MEN1 (0.36) | KMT2AMEN1 | |
| SCHEMBL2229588 | 0.76 | — | — | |
| SCHEMBL20099406 | 0.76 | — | — | |
| SCHEMBL15697261 | 0.76 | TSHR (0.43) | TSHRKMT2AMEN1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073668-A2 | SOLUTION PHASE BIOPOLYMER SYNTHESIS | Köster, Hubert (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055718-A2 | SOLUTION PHASE BIOPOLYMER SYNTHESIS | KOESTER HUBERT (US) | 1999-11-04 | — | — | WO | disclosed |