Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.47 |
| ▸ | RARB | P10826 | 11/20 | 0.47 |
| ▸ | RARG | P13631 | 11/20 | 0.47 |
| ▸ | RARA | P10276 | 10/20 | 0.47 |
| ▸ | RXRB | P28702 | 5/20 | 0.45 |
| ▸ | RXRG | P48443 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755019 | 1.00 | RXRA (0.47) | RXRARARBRARGRARARXRB | |
| SCHEMBL7756532 | 0.91 | RXRA (0.51) | RXRARARBRARGRARARXRB | |
| SCHEMBL7756541 | 0.91 | RXRA (0.51) | RXRARARBRARGRARARXRB | |
| SCHEMBL7755025 | 0.91 | RXRA (0.39) | RXRARARBRARGRARARXRB | |
| SCHEMBL7755311 | 0.90 | RXRA (0.57) | RXRARARBRARGRARARXRB | |
| SCHEMBL7755314 | 0.90 | RXRA (0.57) | RXRARARBRARGRARARXRB | |
| SCHEMBL7789470 | 0.86 | RXRA (0.54) | RXRARARBRARGRARARXRB | |
| SCHEMBL7755022 | 0.86 | RARB (0.53) | RXRARARBRARGRARARXRB | |
| SCHEMBL7789472 | 0.86 | RXRA (0.54) | RXRARARBRARGRARARXRB | |
| SCHEMBL7755028 | 0.86 | RARB (0.53) | RXRARARBRARGRARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077919-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058486-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |