Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 13/20 | 0.54 |
| ▸ | RARB | P10826 | 10/20 | 0.54 |
| ▸ | RARG | P13631 | 10/20 | 0.54 |
| ▸ | RARA | P10276 | 7/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.53 |
| ▸ | RXRB | P28702 | 6/20 | 0.53 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789472 | 1.00 | RXRA (0.54) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7755019 | 0.86 | RXRA (0.47) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7755017 | 0.86 | RXRA (0.47) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7755028 | 0.85 | RARB (0.53) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7755022 | 0.85 | RARB (0.53) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7756532 | 0.85 | RXRA (0.51) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7756541 | 0.85 | RXRA (0.51) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7757722 | 0.85 | RXRA (0.51) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7757729 | 0.85 | RXRA (0.51) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7757695 | 0.82 | RXRA (0.47) | RXRARARBRARGRARACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010037025-A1 | New compounds, their preparation and use | MURRAY ANTHONY (DK) | 2001-11-01 | — | — | US | claimed |
| US-20010037025-A1 | New compounds, their preparation and use | MURRAY ANTHONY (DK) | 2001-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010037025-A1 | New compounds, their preparation and use | GPR119, SLC5A1, SLC5A2 | RXRA 874/4885RARB 1697/4885RARG 1686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.