Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697027 | 0.89 | CPB2 (0.40) | ALDH1A1CPB2LMNAHSD17B10ALOX15 | |
| SCHEMBL21046014 | 0.84 | CPB2 (0.40) | ALDH1A1CPB2LMNAHSD17B10ALOX15 | |
| SCHEMBL4990338 | 0.81 | TSHR (0.42) | ALDH1A1CPB2LMNAHSD17B10ALOX15 | |
| SCHEMBL11822433 | 0.80 | CPB2 (0.40) | ALDH1A1CPB2LMNAHSD17B10ALOX15 | |
| SCHEMBL2875105 | 0.79 | CPB2 (0.60) | ALDH1A1CPB2LMNAHSD17B10ALOX15 | |
| SCHEMBL4989705 | 0.78 | TSHR (0.41) | ALDH1A1CPB2MGAMGAASI | |
| SCHEMBL4613905 | 0.78 | TDP1 (0.50) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL4613459 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL230068 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL16518684 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066729-A1 | AMINOPYRIMIDINONES AS INTERLEUKIN RECEPTOR-ASSOCIATED KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-10 | — | — | WO | disclosed |
| EP-0567949-B1 | Method for removing silyl protecting groups for hydroxy group | TANABE SEIYAKU CO (JP) | 2001-02-21 | — | — | EP | disclosed |
| EP-0937725-A2 | Method for removing the protecting group for hydroxy group | TANABE SEIYAKU CO., LTD. (JP) | 1999-08-25 | — | — | EP | disclosed |
| EP-0559533-B1 | Process for preparing beta-lactam derivative and synthetic intermediate thereof | TANABE SEIYAKU CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5589592-A | Process for preparing β-lactam derivative and synthetic intermediate | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5414081-A | Treating a 1-aza-3-thiabicycloalkane with base and phosphine or phosphite desulfurizing agent, and reacting the product with an active esterifying agent | TANABE SEIYAKU CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| US-5260438-A | With fluorine compound | TANABE SEIYAKU CO., LTD. (JP) | 1993-11-09 | — | — | US | disclosed |
| EP-0567949-A1 | Method for removing the protecting group for hydroxy group | TANABE SEIYAKU CO., LTD. (JP) | 1993-11-03 | — | — | EP | disclosed |
| EP-0559533-A1 | Process for preparing beta-lactam derivative and synthetic intermediate thereof | TANABE SEIYAKU CO., LTD. (JP) | 1993-09-08 | — | — | EP | disclosed |