Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334795 | 0.85 | MAPT (0.44) | MAPTFAAH | |
| SCHEMBL11822441 | 0.84 | MAPT (0.36) | MAPTENPEPACEMMECPA1 | |
| SCHEMBL28889016 | 0.81 | MAPT (0.42) | MAPTBLMSMN1; SMN2FAAH | |
| SCHEMBL335124 | 0.80 | CHRM1 (0.41) | MAPTFAAHACE2 | |
| SCHEMBL335608 | 0.80 | MAPT (0.41) | MAPTMMECPA1RNPEP | |
| SCHEMBL6741172 | 0.79 | MAPT (0.39) | MAPTENPEPFAAH | |
| SCHEMBL10807031 | 0.78 | MAPT (0.40) | MAPTMMECPA1RNPEP | |
| SCHEMBL1010642 | 0.78 | MAPT (0.40) | MAPTFAAH | |
| SCHEMBL6738640 | 0.78 | MAPT (0.38) | MAPTFAAH | |
| SCHEMBL10876637 | 0.77 | MAPT (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567949-B1 | Method for removing silyl protecting groups for hydroxy group | TANABE SEIYAKU CO (JP) | 2001-02-21 | — | — | EP | disclosed |
| EP-0937725-A2 | Method for removing the protecting group for hydroxy group | TANABE SEIYAKU CO., LTD. (JP) | 1999-08-25 | — | — | EP | disclosed |
| US-5260438-A | With fluorine compound | TANABE SEIYAKU CO., LTD. (JP) | 1993-11-09 | — | — | US | disclosed |
| EP-0567949-A1 | Method for removing the protecting group for hydroxy group | TANABE SEIYAKU CO., LTD. (JP) | 1993-11-03 | — | — | EP | disclosed |