SCHEMBL335124

SCHEMBL335124

CCCC(C(=O)O)C(=O)OC(C)CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.41
AKR1A1 P14550 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
ADRA1A P35348 1/20 0.41
HRH1 P35367 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAPT P10636 1/20 0.41
FAAH O00519 1/20 0.38
CA2 P00918 2/20 0.36
MAPK1 P28482 1/20 0.36
CA1 P00915 1/20 0.33
GRIK1 P39086 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28395655 0.92 FAAH (0.40) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL6910766 0.89 CA2 (0.47) TDP1MAPTFAAHCA2MAPK1
SCHEMBL5849651 0.85 FAAH (0.51) MAPTFAAHACE2GPR84FFAR1
SCHEMBL334795 0.85 MAPT (0.44) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL9490145 0.85 MAPT (0.39) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL7056636 0.85 CYP1A2 (0.45) MAPTGRIK1SLC1A3SLC1A2SLC1A1
SCHEMBL11223436 0.84 SMN1; SMN2 (0.36) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL29455985 0.83 CHRM1 (0.44) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL2224240 0.82 MAPT (0.37) TDP1MAPTFAAHCA2MAPK1
SCHEMBL11599817 0.82 MAPT (0.37) TDP1MAPTFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105315390-A Catalyst composition for olefin polymerization and application thereof BEIJING COMBINE TECH CO LTD 2016-02-10 CN claimed
CN-104662027-A Multicomponent mixture of magnesium alkoxide, magnesium halide and alcohol, method for the production thereof and use thereof in a method for producing a catalyst for olefin polymerization INDIAN OIL CORP LTD 2015-05-27 CN claimed
CN-104583219-A Multi component mixture of magnesiumcoholates, magnesiumhalides and alcohol, processes to make them and their use in processes to make olefin polymerization catalyst INDIAN OIL CORP LTD 2015-04-29 CN claimed
CN-104558290-A Components of catalyst for polymerization of olefins and catalyst CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558293-A Catalyst component for olefin polymerization and catalyst CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558291-A Preparation method of catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558292-A Preparation method of catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104513327-A Olefin polymerization catalyst composition and applications thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513332-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513330-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-102557851-B New method for synthesizing tapentadol hydrochloride and analogue of tapentadol hydrochloride ANHUI NEW STAR PHARMACEUTICAL DEV CO LTD 2014-03-26 CN claimed
CN-102557851-A New method for synthesizing tapentadol hydrochloride and analogue of tapentadol hydrochloride ANHUI NEW STAR PHARMACEUTICAL DEV CO LTD 2012-07-11 CN claimed
CN-101830842-A Preparation method of functional amino proline INST SUBTROPICAL AGRI CAS 2010-09-15 CN claimed
CN-109642098-A Electrodepositable coating compositions comprising 1, 1-di-activated vinyl compounds PPG工业俄亥俄公司 2019-04-16 CN disclosed
CN-109476081-A Use the three-dimensional printing method of the vinyl compound activated of 1,1- bis- PPG工业俄亥俄公司 2019-03-15 CN disclosed
CN-105906563-B The synthetic method of 7,8- difluoro-quinoline -3- formic acid 苏州康润医药有限公司 2019-01-22 CN disclosed
EP-0778263-A1 BENZENE COMPOUND AND MEDICINAL USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1997-06-11 EP disclosed
CN-1009199-B The preparation method of 2-substituting group-trimethylene diphosphonate derivatives SYMPHAR SA (CH) 1990-08-15 CN disclosed
CN-85106701-A 2-substituting group-trimethylene diphosphonate derivatives and the preparation method who contains the formula of medicine of this derivative 1987-03-25 CN disclosed
CN-86105901-A Agricultural chemical compound 1987-03-11 CN disclosed