Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15256939 | 0.91 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2AMAPTTSHR | |
| SCHEMBL31337846 | 0.91 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2AMAPTTSHR | |
| SCHEMBL3146763 | 0.89 | ALDH1A1 (0.57) | ALDH1A1LMNAKMT2AMAPTTSHR | |
| SCHEMBL11039202 | 0.87 | ALDH1A1 (0.62) | ALDH1A1LMNAKMT2AMAPTTSHR | |
| SCHEMBL15999899 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNAKMT2AMAPTTSHR | |
| SCHEMBL2418046 | 0.85 | KMT2A (0.65) | ALDH1A1LMNAKMT2AMAPTTSHR | |
| SCHEMBL27927664 | 0.83 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2AMAPTTSHR | |
| SCHEMBL891541 | 0.83 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2AMAPTTSHR | |
| SCHEMBL27782256 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNAKMT2AMAPTTSHR | |
| SCHEMBL11332447 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAKMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664782-B2 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORP (US) | 2001-02-14 | — | — | EP | disclosed |
| EP-0664784-B2 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORP (US) | 1999-09-29 | — | — | EP | disclosed |
| EP-0664782-B1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORP (US) | 1998-03-04 | — | — | EP | disclosed |
| EP-0664783-B1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORP (US) | 1998-02-04 | — | — | EP | disclosed |
| EP-0664781-B1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORP (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0664784-B1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORP (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5442117-A | Enantiomeric resolution | ALBEMARLE CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0664781-A1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORPORATION (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0664782-A1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORPORATION (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0664783-A1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORPORATION (US) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008934-A1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORPORATION (US) | 1994-04-28 | — | — | WO | disclosed |
| WO-1994008936-A1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORPORATION (US) | 1994-04-28 | — | — | WO | disclosed |
| WO-1994008935-A1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORPORATION (US) | 1994-04-28 | — | — | WO | disclosed |
| WO-1994008937-A1 | ENANTIOMERIC RESOLUTION | ALBEMARLE CORPORATION (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5278337-A | Enantiomeric resolution of aryl-substituted aliphatic carboxylic acids | ETHYL CORPORATION (US) | 1994-01-11 | — | — | US | disclosed |
| US-5260482-A | Enantiomeric resolution | ETHYL CORPORATION (US) | 1993-11-09 | — | — | US | disclosed |
| US-5256816-A | Enantiomeric resolution | ETHYL CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |
| US-5248813-A | Enantiomeric resolution | ETHYL CORPORATION (US) | 1993-09-28 | — | — | US | disclosed |
| US-4808620-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIALLERGENS, ANTIARTHRITIC, ANTIRHEUMATIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0254241-A1 | Pyrazolopyridine compounds, their preparation and use | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-27 | — | — | EP | disclosed |