SCHEMBL7755299

SCHEMBL7755299

N#Cc1cc([C]=O)ccc1F

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 2/20 0.41
AR P10275 1/20 0.40
GRM4 Q14833 1/20 0.38
CNR2 P34972 1/20 0.38
PTP4A3 O75365 1/20 0.37
PGR P06401 4/20 0.36
ACLY P53396 1/20 0.35
BLM P54132 1/20 0.35
WRN Q14191 1/20 0.35
CYP11B1 P15538 2/20 0.34
CYP11B2 P19099 2/20 0.34
FFAR1 O14842 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
KIF11 P52732 1/20 0.33
VNN1 O95497 1/20 0.33
PLA2G7 Q13093 1/20 0.33
P4HB P07237 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL924361 0.85 TRPV4 (0.45) TRPV4ARGRM4CNR2PTP4A3
SCHEMBL3633872 0.79 TRPV4 (0.41) TRPV4ARGRM4CNR2PTP4A3
SCHEMBL22031496 0.79 EGFR (0.31)
SCHEMBL16961256 0.79 TRPV4 (0.41) TRPV4ARGRM4CNR2PTP4A3
SCHEMBL23302859 0.75 CYP1A2 (0.37)
SCHEMBL97003 0.75 GRM5 (0.46) FFAR1FFAR4
SCHEMBL4466578 0.74 TRPV4 (0.43) TRPV4ARGRM4CNR2PTP4A3
SCHEMBL16541681 0.73 TRPV4 (0.39) TRPV4ARGRM4CNR2PTP4A3
SCHEMBL74807 0.73 TRPV4 (0.46) TRPV4ARGRM4CNR2PTP4A3
SCHEMBL2794339 0.72 FFAR1 (0.36) TRPV4ARGRM4PGRCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0748850-B1 Dyestuffs, process for their preparation and their use CIBA SC HOLDING AG (CH) 2001-07-04 EP disclosed
EP-0828870-B1 SPIN DYEING PROCESS WITH DYEING SALTS DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-02-14 EP disclosed
EP-0625551-B1 Mixtures of dyes, process for their preparation and the use thereof CIBA GEIGY AG (CH) 1999-09-29 EP disclosed
EP-0631008-B1 Process for the washing of printings or dyeings on cellulose containing textile materials CIBA GEIGY AG (CH) 1999-08-18 EP disclosed
US-5938796-A Alkali system for dyeing cellulosic textiles by padding methods DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-08-17 US disclosed
US-5931975-A TRIAZINE REACTIVE DYES CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-03 US disclosed
US-5925746-A HEAT RESISTANT DISAZO DYES WHICH PRODUCE COLORFAST PINK SHADES ON COTTON CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-07-20 US disclosed
EP-0889098-A2 Azo dyes, process for their preparation and the use thereof Ciba SC Holding AG (CH) 1999-01-07 EP disclosed
US-5851239-A Spin dyeing process with dyeing salts DYSTAR TEXTILFARBEN GMBH & CO. (DE) 1998-12-22 US disclosed
EP-0684292-B1 Reactive dyes for inkjet printing and aqueous ink compositions containing the same DYSTAR TEXTILFARBEN GMBH & CO (DE) 1998-11-18 EP disclosed
EP-0181292-A2 Process for the continuous trichromatic dyeing of synthetic polyamide materials CIBA-GEIGY AG (CH) 1986-05-14 EP disclosed
EP-0181293-A2 Process for dyeing synthetic polyamide materials with anthrachinone reactive dyes CIBA-GEIGY AG (CH) 1986-05-14 EP disclosed
US-4588411-A Long-shelflife print containing reactive dye and alkali acetate pastes and their use CIBA-GEIGY CORPORATION (US) 1986-05-13 US disclosed
EP-0179019-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1986-04-23 EP disclosed
EP-0178255-A1 Process for fixing dyeings or printings CIBA-GEIGY AG (CH) 1986-04-16 EP disclosed
EP-0177449-A1 Process for printing cellulosic fibres CIBA-GEIGY AG (CH) 1986-04-09 EP disclosed
EP-0144093-A1 Storage-stable printing pastes and their use CIBA-GEIGY AG (CH) 1985-06-12 EP disclosed
EP-0131545-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-01-16 EP disclosed
US-4400504-A DYEING AND PRINTING CELLULOSE AND POLYAMIDE AND-URETHANE FIBERS; TRIAZINE, PYRIDINE AND PYRIMIDINE DYES BAYER AKTIENGESELLSCHAFT (DE) 1983-08-23 US disclosed
EP-0053743-A2 Reactive dioxazine dyestuffs, process for their preparation and their use in dyeing and printing fibrous materials containing hydroxyle or amide groups BAYER AG (DE) 1982-06-16 EP disclosed