Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2198533 | 0.83 | CYP11B2 (0.46) | TRPV4CYP11B1CYP11B2ARMAOA | |
| SCHEMBL1514274 | 0.82 | CYP11B1 (0.57) | CYP11B1CYP11B2MAOBCNR2ALDH1A1 | |
| SCHEMBL573864 | 0.82 | MAOB (0.53) | TRPV4CYP11B1CYP11B2ARMAOA | |
| SCHEMBL21116203 | 0.80 | USP8 (0.42) | TRPV4CYP11B1CYP11B2MAOAMAOB | |
| SCHEMBL57346 | 0.80 | TRPV4 (0.61) | TRPV4CYP11B1CYP11B2ARMAOA | |
| SCHEMBL30919072 | 0.80 | TRPV4 (0.61) | TRPV4CYP11B1CYP11B2ARMAOA | |
| SCHEMBL28295046 | 0.79 | KDM4E (0.46) | TRPV4CYP11B1CYP11B2MAOAMAOB | |
| SCHEMBL481131 | 0.78 | CYP2A6 (0.46) | TRPV4CYP11B1CYP11B2ARMAOA | |
| SCHEMBL29998893 | 0.78 | CYP2A6 (0.46) | TRPV4CYP11B1CYP11B2ARMAOA | |
| Ethylene SCHEMBL27960950 | 0.78 | MAOB (0.50) | TRPV4CYP11B1CYP11B2ARMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 815 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743438-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS | Aarti Industries Limited (IN) | 2026-05-20 | — | — | EP | claimed |
| EP-4665705-A1 | A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS | Aarti Industries Limited (IN) | 2025-12-24 | — | — | EP | claimed |
| WO-2025068995-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS | AARTI INDUSTRIES LIMITED (IN) | 2025-04-03 | — | — | WO | claimed |
| WO-2024171098-A1 | A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS | AARTI INDUSTRIES LIMITED (IN) | 2024-08-22 | — | — | WO | claimed |
| CN-117790893-A | Electrolyte and lithium battery containing same | 蜂巢能源科技股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117326927-A | Preparation method of 2,5-bis (2, 2-trifluoroethoxy) benzoic acid | 清源创新实验室 | 2024-01-02 | — | — | CN | claimed |
| CN-109952289-B | TRPV4 antagonists | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-111606841-B | Deep blue photo-thermal crosslinking type thermal activation delayed fluorescence material and preparation method and application thereof | 山西穿越光电科技有限责任公司 | 2022-07-19 | — | — | CN | claimed |
| CN-110343223-B | Benzoxazine resin containing alkynyl and aryl ether nitrile structure, composite material and preparation method thereof | 辽宁鲸苇科技有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-111530311-B | Preparation method of monolithic poly (arylene ether nitrile) bipolar membrane containing corrole water dissociation catalytic group | 福建师范大学 | 2022-03-15 | — | — | CN | claimed |
| US-9790206-B2 | Intermediates for use in the preparation of indazole derivatives and processes for the preparation thereof | ARRAY BIOPHARMA INC. (US) | 2017-10-17 | — | — | US | claimed |
| EP-2961744-B1 | INTERMEDIATES FOR USE IN THE PREPARATION OF INDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | ARRAY BIOPHARMA INC (US) | 2017-06-28 | — | — | EP | claimed |
| CN-106633059-A | Ethynyl terminated polyarylene ether nitrile imide resin and preparation method thereof | 沈阳航空航天大学 | 2017-05-10 | — | — | CN | claimed |
| CN-106496558-A | One kind can response type poly (arylene ether nitrile) imide resin and preparation method thereof | 沈阳航空航天大学 | 2017-03-15 | — | — | CN | claimed |
| US-20160002210-A1 | INTERMEDIATES FOR USE IN THE PREPARATION OF INDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | ARRAY BIOPHARMA INC. (US) | 2016-01-07 | — | — | US | claimed |
| EP-2961744-A1 | INTERMEDIATES FOR USE IN THE PREPARATION OF INDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Array Biopharma, Inc. (US) | 2016-01-06 | — | — | EP | claimed |
| CN-105073739-A | Intermediates for use in the preparation of indazole derivatives and processes for the preparation thereof | ARRAY BIOPHARMA INC | 2015-11-18 | — | — | CN | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| WO-2014134313-A1 | INTERMEDIATES FOR USE IN THE PREPARATION OF INDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | ARRAY BIOPHARMA INC. (US) | 2014-09-04 | — | — | WO | claimed |
| US-20110207000-A1 | Nitrile additive for non-aqueous electrolyte rechargeable electrochemical cells | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY, THE | 2011-08-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002210-A1 | INTERMEDIATES FOR USE IN THE PREPARATION OF INDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CYP3A7, CYP3A5, CYP3A43 | TRPV4 4490/4885CA3 3563/4885CA6 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.