Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | EP300 | Q09472 | 2/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 2/20 | 0.37 |
| ▸ | PGK2 | P07205 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9168389 | 0.88 | ACP3 (0.70) | ACP3ALDH1A1PGK1PGK2SMN1; SMN2 | |
| SCHEMBL8824563 | 0.78 | ACP3 (0.58) | ACP3HPGDTSHRPGK1PGK2 | |
| SCHEMBL233490 | 0.76 | FDPS (0.56) | ACP3FDPSPGK1PGK2SMN1; SMN2 | |
| SCHEMBL28469180 | 0.76 | IDO1 (0.54) | IDO1EP300KAT8HDAC3KAT2B | |
| SCHEMBL916960 | 0.75 | ACP3 (0.54) | ACP3ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL31574390 | 0.74 | IDO1 (0.47) | IDO1EP300KAT8HDAC3KAT2B | |
| SCHEMBL1562761 | 0.74 | IDO1 (0.47) | IDO1EP300KAT8HDAC3KAT2B | |
| SCHEMBL7755649 | 0.74 | CTSB (0.54) | ACP3ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL7755658 | 0.74 | CTSB (0.54) | ACP3ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL38654397 | 0.73 | IDO1 (0.50) | IDO1EP300KAT8HDAC3KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769015-B1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-5716944-A | USEFUL AS PROPHYLACTIC AND THERAPEUTIC AGENTS OF VARIOUS METABOLIC BONE DISEASES SUCH AS OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0769015-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001267-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-18 | — | — | WO | disclosed |