SCHEMBL7755791

SCHEMBL7755791

COC1(C=CC(=O)OC(=O)C=CC2(OC)CCCC2c2cc3c(cc2C)C(C)(C)CCC3(C)C)CCCC1c1ccc2c(c1)C(C)(C)CCC2(C)C

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RXRA P19793 20/20 0.49
RARB P10826 4/20 0.49
RARG P13631 4/20 0.49
RXRB P28702 4/20 0.33
RXRG P48443 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7755796 0.92 RXRA (0.55) RXRARARBRARGRXRBRXRG
SCHEMBL7755783 0.92 RXRA (0.55) RXRARARBRARGRXRBRXRG
SCHEMBL7755781 0.92 RXRA (0.55) RXRARARBRARGRXRBRXRG
SCHEMBL7755808 0.83 RXRA (0.47) RXRARARBRARGRXRBRXRG
SCHEMBL7755812 0.83 RXRA (0.47) RXRARARBRARGRXRBRXRG
SCHEMBL7755803 0.83 RXRA (0.47) RXRARARBRARGRXRBRXRG
SCHEMBL7755832 0.83 RXRA (0.60) RXRARARBRARGRXRBRXRG
SCHEMBL7755837 0.83 RXRA (0.60) RXRARARBRARGRXRBRXRG
SCHEMBL7755829 0.83 RXRA (0.60) RXRARARBRARGRXRBRXRG
SCHEMBL7757702 0.70 RXRA (0.45) RXRARARBRARGRXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1077920-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-02-28 EP disclosed
WO-1999058487-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1999-11-18 WO disclosed