Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.45 |
| ▸ | RARG | P13631 | 5/20 | 0.45 |
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | RXRB | P28702 | 4/20 | 0.35 |
| ▸ | RXRG | P48443 | 4/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754550 | 0.81 | RXRA (0.52) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7756268 | 0.80 | RXRA (0.52) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7755783 | 0.75 | RXRA (0.55) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7755781 | 0.75 | RXRA (0.55) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7755796 | 0.75 | RXRA (0.55) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7757741 | 0.74 | RARG (0.36) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7788780 | 0.72 | RXRA (0.56) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7756218 | 0.70 | RXRA (0.49) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7755791 | 0.70 | RXRA (0.49) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7755808 | 0.67 | RXRA (0.47) | RXRARARGRARBRXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077920-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058487-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |