SCHEMBL7755863

SCHEMBL7755863

COC1(C(C)=CC(=O)O)CCC(c2ccc3c(c2)C(C)(C)CCC3(C)C)C1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RXRA P19793 19/20 0.48
RARB P10826 8/20 0.48
RARG P13631 8/20 0.48
RXRG P48443 10/20 0.43
RXRB P28702 9/20 0.43
RARA P10276 4/20 0.43
PPARG P37231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7755855 1.00 RXRA (0.48) RXRARARBRARGRXRGRXRB
SCHEMBL7781836 0.83 RXRA (0.45) RXRARARBRARGRXRGRXRB
SCHEMBL7781833 0.83 RXRA (0.45) RXRARARBRARGRXRGRXRB
SCHEMBL7781814 0.72 RARB (0.43) RXRARARBRARGRXRGRXRB
SCHEMBL7790860 0.72 RXRA (0.52) RXRARARBRARGRXRGRXRB
SCHEMBL7786467 0.70 RXRA (0.54) RXRARARBRARGRXRGRXRB
SCHEMBL7786465 0.70 RXRA (0.54) RXRARARBRARGRXRGRXRB
SCHEMBL7781816 0.70 RARB (0.39) RXRARARBRARGRXRGRXRB
SCHEMBL7751744 0.69 RXRA (0.50) RXRARARBRARGRXRGRXRB
SCHEMBL7751739 0.69 RXRA (0.50) RXRARARBRARGRXRGRXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010037025-A1 New compounds, their preparation and use MURRAY ANTHONY (DK) 2001-11-01 US claimed
US-20010037025-A1 New compounds, their preparation and use MURRAY ANTHONY (DK) 2001-11-01 US disclosed
EP-1077919-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-02-28 EP disclosed
WO-1999058486-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1999-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037025-A1 New compounds, their preparation and use GPR119, SLC5A1, SLC5A2 RXRA 874/4885RARB 1697/4885RARG 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.