Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16149851 | 0.84 | HTR7 (0.47) | HTR7PTPN1 | |
| SCHEMBL18227494 | 0.84 | HTR7 (0.47) | HTR7PTPN1 | |
| SCHEMBL14141070 | 0.82 | PTPN1 (0.35) | HTR7PTPN1 | |
| SCHEMBL27840595 | 0.82 | PTPN1 (0.35) | HTR7PTPN1 | |
| SCHEMBL25028174 | 0.82 | PTPN1 (0.35) | HTR7PTPN1 | |
| SCHEMBL576941 | 0.81 | HTR7 (0.43) | HTR7PTPN1MAOA | |
| SCHEMBL8943222 | 0.80 | HTR7 (0.34) | HTR7PTPN1CDC25B | |
| SCHEMBL19979019 | 0.80 | MAOA (0.32) | MAOAMAOB | |
| SCHEMBL22236637 | 0.80 | — | — | |
| SCHEMBL14146988 | 0.80 | HTR7 (0.32) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080085-A1 | PREPARATION OF CIS-6,6-DIMETHYL-3-OXA-BICYCLO 3.1.0]HEXAN-2-ONE | ZENECA LIMITED (GB) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999054324-A1 | PREPARATION OF CIS-6,6-DIMETHYL-3-OXA-BICYCLO[3.1.0]HEXAN-2-ONE | ZENECA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |