SCHEMBL7755906

SCHEMBL7755906

O=S(=O)(O)c1cccc(SP(Sc2cccc(S(=O)(=O)O)c2)Sc2cccc(S(=O)(=O)O)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 3/20 0.50
HSD17B10 Q99714 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.45
ANXA2 P07355 1/20 0.39
S100A10 P60903 1/20 0.39
NAPRT Q6XQN6 1/20 0.37
CASR P41180 2/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
LMNA P02545 1/20 0.34
SNCA P37840 1/20 0.34
SENP3 Q9H4L4 2/20 0.34
SENP2 Q9HC62 2/20 0.34
SENP1 Q9P0U3 2/20 0.34
SUMO2 P61956 1/20 0.34
SUMO1 P63165 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
GAA P10253 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10505085 0.82 HSD17B10 (0.55) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL7755598 0.81 ALDH1A1 (0.45) ALDH1A1HSD17B10TDP1ANXA2S100A10
SCHEMBL13346841 0.80 ALDH1A1 (0.53) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL26610860 0.78 TSHR (0.52) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL28261327 0.77 TSHR (0.50) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL151444 0.76 ALDH1A1 (0.70) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL1563586 0.76 ALDH1A1 (0.70) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL10884986 0.74 TSHR (0.47) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL9550121 0.74 ALDH1A1 (0.67) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL5873323 0.74 ALDH1A1 (0.67) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001043874-A1 ORGANIC POLYMERIC SUPPORTS WITH MONO- OR BI-DENTATE LIGANDS AND THEIR USE AS A SUPPORTED CATALYST SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) 2001-06-21 WO disclosed