SCHEMBL7755598

SCHEMBL7755598

O=S(=O)(Cl)c1cccc(SP(Sc2cccc(S(=O)(=O)Cl)c2)Sc2cccc(S(=O)(=O)Cl)c2)c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ANXA2 P07355 1/20 0.39
S100A10 P60903 1/20 0.39
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 1/20 0.31
CA12 O43570 1/20 0.31
CA4 P22748 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7755906 0.81 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1ANXA2S100A10
SCHEMBL30306605 0.78 HPGD (0.51) ALDH1A1HSD17B10TDP1ANXA2S100A10
SCHEMBL20048746 0.78 HPGD (0.51) ALDH1A1HSD17B10TDP1ANXA2S100A10
SCHEMBL56599 0.76 ALDH1A1 (0.65) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL13913369 0.72 ALDH1A1 (0.39) ALDH1A1HSD17B10TDP1ANXA2S100A10
SCHEMBL10408548 0.70 ALDH1A1 (0.56) ALDH1A1HSD17B10TDP1CA1CA2
SCHEMBL2264686 0.70 ALDH1A1 (0.56) ALDH1A1HSD17B10TDP1ANXA2S100A10
SCHEMBL29422524 0.69 ALDH1A1 (0.54) ALDH1A1HSD17B10TDP1
SCHEMBL16000 0.69 ALDH1A1 (0.54) ALDH1A1HSD17B10TDP1
SCHEMBL1584550 0.67 KMT2A (0.55) ALDH1A1HSD17B10TDP1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001043874-A1 ORGANIC POLYMERIC SUPPORTS WITH MONO- OR BI-DENTATE LIGANDS AND THEIR USE AS A SUPPORTED CATALYST SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) 2001-06-21 WO disclosed