SCHEMBL7756097

SCHEMBL7756097

CCCCc1cccc([SiH3])c1CCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.39
ALOX5 P09917 1/20 0.39
PTGS2 P35354 1/20 0.39
BID P55957 3/20 0.37
MCL1 Q07820 3/20 0.37
BCL2L1 Q07817 2/20 0.37
BAK1 Q16611 2/20 0.37
KAT8 Q9H7Z6 2/20 0.37
PPARA Q07869 2/20 0.37
PPARG P37231 1/20 0.37
EP300 Q09472 1/20 0.37
KAT2A Q92830 1/20 0.37
KAT2B Q92831 1/20 0.37
KAT5 Q92993 1/20 0.37
SAE1 Q9UBE0 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
TYR P14679 1/20 0.36
CYSLTR2 Q9NS75 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9644863 0.92 LIPG (0.49) LIPGALOX5PTGS2BIDMCL1
SCHEMBL819273 0.85 LIPG (0.45) LIPGALOX5PTGS2BIDMCL1
Water SCHEMBL27341058 0.83 LIPG (0.44) LIPGALOX5PTGS2BIDMCL1
Ammonia Solution, Strong SCHEMBL9810933 0.83 LIPG (0.44) LIPGALOX5PTGS2BIDMCL1
SCHEMBL10321006 0.82 KCNH2 (0.41) LIPGALOX5PTGS2BIDMCL1
SCHEMBL3886767 0.82 TYR (0.41) LIPGALOX5CYP3A4CYP2D6CYP2C9
SCHEMBL28355115 0.81 LIPG (0.42) LIPGALOX5PTGS2BIDMCL1
SCHEMBL5981800 0.81 LIPG (0.47) LIPGALOX5PTGS2BIDMCL1
SCHEMBL10319951 0.80 KCNH2 (0.43) LIPGALOX5PTGS2BIDMCL1
SCHEMBL10319478 0.80 KCNH2 (0.43) LIPGALOX5PTGS2BIDMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001060932-A1 ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2001-08-23 WO claimed
WO-2022074177-A1 DYNAMIC KINETIC RESOLUTION OF ALCOHOLS BY ENANTIOSELECTIVE SILYLATION Technische Universität Berlin (DE) 2022-04-14 WO disclosed
EP-3981773-A1 DYNAMIC KINETIC RESOLUTION OF ALCOHOLS BY ENANTIOSELECTIVE SILYLATION Technische Universität Berlin (DE) 2022-04-13 EP disclosed
WO-2001060932-A1 ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2001-08-23 WO disclosed
EP-0191260-B1 PENTACOORDINATED SILICON COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PREPARING ORGANOSILANES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-05-31 EP disclosed
US-4617413-A Pentacoordinate silicon complexes, the process for their preparation and their application to the preparation of organosilanes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1986-10-14 US disclosed
EP-0191260-A1 Pentacoordinated silicon complexes, process for their preparation and their use in preparing organosilanes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-08-20 EP disclosed