SCHEMBL3886767

SCHEMBL3886767

CCCCc1ccc([SiH3])c(CCCC)c1CCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.41
CTRC Q99895 1/20 0.38
HTT P42858 2/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CYP3A4 P08684 2/20 0.35
TYMP P19971 2/20 0.35
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
ALOX5 P09917 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LIPG Q9Y5X9 1/20 0.32
SKP2 Q13309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4633219 0.87 TYR (0.50) TYRCTRCHTTNPC1HPGD
SCHEMBL30044969 0.87 TYR (0.50) TYRCTRCHTTNPC1HPGD
SCHEMBL12815493 0.82 CTRC (0.42) TYRCTRCHTTNPC1HPGD
SCHEMBL7756097 0.82 LIPG (0.39) TYRHTTNPC1HPGDMAPK1
SCHEMBL31230428 0.80 TYR (0.53) TYRCTRCHTTCYP3A4TYMP
SCHEMBL1133572 0.80 TYR (0.53) TYRCTRCHTTCYP3A4TYMP
SCHEMBL23923950 0.79 MPO (0.32)
SCHEMBL4190211 0.79
SCHEMBL187980 0.79 TYR (0.41) TYRCTRCHTTNPC1HPGD
SCHEMBL28163569 0.79 TYR (0.41) TYRCTRCHTTNPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
US-7352065-B2 Semiconductor devices having amorphous silicon-carbon dielectric and conducting layers NANODYNAMICS, INC. (US) 2008-04-01 US disclosed
US-20060160372-A1 Method and apparatus for fabricating low-k dielectrics, conducting films, and strain-controlling conformable silica-carbon materials NANO-APPLICATIONS HOLDINGS B.V. (NL) 2006-07-20 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20060005900-A1 High-alloy metals reinforced by diamond-like framework and method for making the same DORFMAN BENJAMIN R 2006-01-12 US disclosed
US-20050163985-A1 Synergetic SP-SP2-SP3 carbon materials and deposition methods thereof NANO-APPLICATIONS HOLDINGS B.V. (NL) 2005-07-28 US disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed
EP-0191260-B1 PENTACOORDINATED SILICON COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PREPARING ORGANOSILANES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-05-31 EP disclosed
US-4617413-A Pentacoordinate silicon complexes, the process for their preparation and their application to the preparation of organosilanes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1986-10-14 US disclosed
EP-0191260-A1 Pentacoordinated silicon complexes, process for their preparation and their use in preparing organosilanes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-08-20 EP disclosed