Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755087 | 0.95 | ADRB2 (0.35) | ALOX5ADRB2ADRB1ADRB3 | |
| SCHEMBL7758297 | 0.91 | BACE1 (0.34) | ALOX5BCHEBACE1 | |
| SCHEMBL4190007 | 0.83 | BACE1 (0.40) | ALOX5BCHEBACE1 | |
| SCHEMBL722594 | 0.83 | IGF1R (0.36) | ALOX5ADRB2ADRB1ADRB3BCHE | |
| SCHEMBL11296010 | 0.83 | ALDH1A1 (0.38) | ALOX5BACE1 | |
| SCHEMBL11300811 | 0.82 | IGF1R (0.35) | ALOX5BCHEBACE1 | |
| SCHEMBL7758292 | 0.80 | SLC6A2 (0.42) | — | |
| SCHEMBL15541962 | 0.80 | APP (0.37) | ALOX5 | |
| SCHEMBL3721174 | 0.79 | IGF1R (0.39) | — | |
| SCHEMBL15541469 | 0.79 | TRPV1 (0.34) | ALOX5ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077912-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | disclosed |