Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA3 | P32297 | 6/20 | 0.71 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.71 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.69 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.62 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.62 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7753623 | 0.98 | CHRNA3 (0.69) | CHRNA3CHRNB2CHRNA4CHRNA1CHRNB4 | |
| SCHEMBL7753657 | 0.83 | CHRNB2 (0.70) | CHRNA3CHRNB2CHRNA4CHRNA7MEN1 | |
| SCHEMBL7756327 | 0.82 | CHRNB2 (1.00) | CHRNA3CHRNB2CHRNA4CHRNA7MEN1 | |
| Hydrochloric Acid SCHEMBL7757792 | 0.81 | CHRNB2 (0.68) | CHRNA3CHRNB2CHRNA4CHRNA7MEN1 | |
| SCHEMBL7757357 | 0.79 | CHRNB2 (0.56) | CHRNA3CHRNB2CHRNA4CHRNA1CHRNB4 | |
| SCHEMBL7758362 | 0.78 | CHRNA3 (0.56) | CHRNA3CHRNB2CHRNA4CHRNA1CHRNB4 | |
| SCHEMBL7759608 | 0.76 | CHRNB2 (0.70) | CHRNA3CHRNB2CHRNA4CHRNA7MEN1 | |
| SCHEMBL7757799 | 0.76 | CHRNB2 (0.59) | CHRNA3CHRNB2CHRNA4CHRNA1CHRNB4 | |
| SCHEMBL7753648 | 0.76 | CHRNB2 (0.62) | CHRNA3CHRNB2CHRNA4CHRNA1CHRNB4 | |
| Hydrochloric Acid SCHEMBL7759630 | 0.74 | CHRNB2 (0.58) | CHRNA3CHRNB2CHRNA4CHRNA1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049690-A1 | 9-AZABICYCLO[4.2.1]NON-2-ENE DERIVATIVES AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTORS | UNIVERSITY OF BRISTOL (GB) | 2001-07-12 | — | — | WO | disclosed |