Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL7756519

COc1ccc2c(C(=S)Oc3ccc(F)cc3)c3ccccc3[n+](C)c2c1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.37
ACHE P22303 10/20 0.35
TP53 P04637 1/20 0.34
HSP90AA1 P07900 1/20 0.33
G6PD P11413 1/20 0.33
PKM P14618 1/20 0.31
KEAP1 Q14145 2/20 0.31
NFE2L2 Q16236 2/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL7025215 0.92 ACHE (0.38) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL7755730 0.90 KCNH2 (0.44) KCNH2ACHETP53HSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL7752445 0.84 ACHE (0.36) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL7756534 0.84 KCNH2 (0.41) KCNH2ACHEPKMGAA
Trifluoromethanesulfonic Acid SCHEMBL9090449 0.83 ACHE (0.35) KCNH2ACHEKEAP1NFE2L2
Trifluoromethanesulfonic Acid SCHEMBL7787040 0.80 ACHE (0.39) KCNH2ACHETP53KMT2A
Trifluoromethanesulfonic Acid SCHEMBL7795306 0.80 KCNH2 (0.38) KCNH2ACHEHSP90AA1G6PDKMT2A
Trifluoromethanesulfonic Acid SCHEMBL7793794 0.79 KCNH2 (0.35) KCNH2ACHEHSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL7755167 0.78 ACHE (0.33) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL7705513 0.78 KCNH2 (0.37) KCNH2ACHEHSP90AA1G6PDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0755457-B1 Novel Aryl-N-Alkylacridanthiocarboxylate derivatives useful for chemiluminescent detection LUMIGEN INC (US) 2001-02-21 EP disclosed
EP-0755457-A4 NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION LUMIGEN INC (US) 1997-07-16 EP disclosed
EP-0755457-A1 NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION LUMIGEN, INC. (US) 1997-01-29 EP disclosed
US-5523212-A OXIDATION WITH PEROXIDE AND PEROXIDASE TO EXCITED ACRIDONE DERIVATIVE; DETECTING PROTEINS, HAPTENS, ANTIBODIES, ENZYMES LUMIGEN, INC. (US) 1996-06-04 US disclosed
WO-1995028495-A1 NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION LUMIGEN, INC. (US) 1995-10-26 WO disclosed