Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL7703831 | 0.90 | GABRA1 (0.37) | KCNH2ABHD6ACHEGABRA1GABRG2 | |
| Trifluoromethanesulfonic Acid SCHEMBL7703955 | 0.89 | ABHD6 (0.40) | KCNH2ABHD6ACHEMAPTHSP90AA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7702814 | 0.88 | ACHE (0.35) | KCNH2ABHD6ACHEHSP90AA1GABRA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7702382 | 0.84 | GABRA1 (0.34) | ACHEGABRA1GABRG2GABRB3GABRA5 | |
| Trifluoromethanesulfonic Acid SCHEMBL7706738 | 0.83 | KCNH2 (0.35) | KCNH2ACHEGABRA1GABRG2GABRB3 | |
| Trifluoromethanesulfonic Acid SCHEMBL7795306 | 0.83 | KCNH2 (0.38) | KCNH2ACHEMAPTHSP90AA1G6PD | |
| Trifluoromethanesulfonic Acid SCHEMBL7793794 | 0.81 | KCNH2 (0.35) | KCNH2ACHEHSP90AA1G6PDPOLB | |
| Trifluoromethanesulfonic Acid SCHEMBL7697990 | 0.80 | ABHD6 (0.39) | KCNH2ABHD6ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL2996949 | 0.78 | ACHE (0.42) | KCNH2ACHELMNA | |
| Trifluoromethanesulfonic Acid SCHEMBL7756519 | 0.78 | KCNH2 (0.37) | KCNH2ACHEHSP90AA1G6PDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915851-B1 | DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS | NEDERLANDEN STAAT (NL) | 2002-03-20 | — | — | EP | disclosed |
| US-6030803-A | FOR USE AS SUBSTRATE IN PEROXIDASE ASSAYS; ALPHA-CARBON ATOM OF THE ESTER ALKYL GROUP IS AN ALIPHATIC CARBON ATOM | DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGESZONHEID EN CULTUUR (NL) | 2000-02-29 | — | — | US | disclosed |