SCHEMBL7756852

SCHEMBL7756852

CC(C)(C)OOC(=O)c1ccccc1C(=O)Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.58
ALDH1A1 P00352 6/20 0.58
TDP1 Q9NUW8 2/20 0.58
HSD17B10 Q99714 2/20 0.58
ALOX15 P16050 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 2/20 0.35
CYP3A4 P08684 2/20 0.35
ELANE P08246 1/20 0.35
TP53 P04637 1/20 0.35
MAPK1 P28482 1/20 0.35
CFTR P13569 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
NPC1 O15118 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155434 0.91 TSHR (0.68) TSHRALDH1A1TDP1HSD17B10L3MBTL1
SCHEMBL29631091 0.91 TSHR (0.68) TSHRALDH1A1TDP1HSD17B10L3MBTL1
SCHEMBL9015728 0.90 TSHR (0.46) TSHRALDH1A1TDP1HSD17B10ALOX15
Benzene SCHEMBL12472151 0.89 TSHR (0.71) TSHRALDH1A1TDP1HSD17B10ALOX15
SCHEMBL11655234 0.89 TSHR (0.66) TSHRALDH1A1TDP1HSD17B10L3MBTL1
SCHEMBL2477857 0.84 ALDH1A1 (0.65) TSHRALDH1A1TDP1HSD17B10ALOX15
SCHEMBL155433 0.84 TSHR (0.59) TSHRALDH1A1TDP1HSD17B10L3MBTL1
SCHEMBL2439254 0.84 TSHR (0.59) TSHRALDH1A1TDP1HSD17B10L3MBTL1
SCHEMBL9103099 0.83 TSHR (0.43) TSHRALDH1A1TDP1HSD17B10ALOX15
SCHEMBL7140474 0.82 TSHR (0.86) TSHRALDH1A1TDP1HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3952041-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1976-04-20 US claimed
EP-0850927-B1 Novel oxalic acid peroxide compositions and their uses ATOFINA CHEM INC (US) 2001-03-14 EP disclosed
US-5866712-A POLYMERIZATION AND CURING CATALYSTS ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-02-02 US disclosed
EP-0850927-A1 Novel oxalic acid peroxide compositions and uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed
EP-0472819-B1 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ATOCHEM NORTH AMERICA ELF (US) 1996-08-21 EP disclosed
US-5457162-A Catalyst for addition polymerization, curing and crosslinking ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-10-10 US disclosed
US-5451654-A Addition polymerization catalyst ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-09-19 US disclosed
US-5399630-A Process for curing polymers using amino or hydrazino peroxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-03-21 US disclosed
EP-0355733-B1 Amino or hydrazino peroxides, derivatives and their uses ATOCHEM NORTH AMERICA (US) 1995-02-08 EP disclosed
US-5387654-A Hydroxy-peroxides and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-02-07 US disclosed
US-5304649-A Curing agent for unsaturated polyesters ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-19 US disclosed
US-5272219-A Process for preparing amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-12-21 US disclosed
EP-0472819-A2 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-03-04 EP disclosed
US-5039754-A Block copolymer;compatibilizing polymer blends and alloy ATOCHEM NORTH AMERICA, INC. (US) 1991-08-13 US disclosed
US-4956416-A CURING UNSATURATED POLYESTERS; ADDITION POLYMERIZATION CATALYSTS; COAVALENTLY BOUND PERFORMANCE ADDITIVE FUNCTIONS; GRAFT AND BLOCK POLYMERS; SELF-CURING ATOCHEM NORTH AMERICA, INC. (US) 1990-09-11 US disclosed
EP-0381135-A2 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA, INC. (US) 1990-08-08 EP disclosed
EP-0355733-A1 Amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1990-02-28 EP disclosed
US-4304882-A Polymer from peroxy compounds containing acylating groups PENNWALT CORPORATION (US) 1981-12-08 US disclosed
US-3991109-A POLYMERIZATION INITIATORS PENNWALT CORPORATION (US) 1976-11-09 US disclosed
US-3952041-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1976-04-20 US disclosed