Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030231 | 0.92 | TSHR (0.50) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL6162550 | 0.86 | TSHR (0.44) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL7756852 | 0.83 | TSHR (0.58) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL22773852 | 0.83 | ADRB2 (0.45) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL27458878 | 0.83 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL4612232 | 0.82 | ELANE (0.49) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL27927289 | 0.81 | ALDH1A1 (0.57) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL9015728 | 0.78 | TSHR (0.46) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL23922673 | 0.77 | ELANE (0.37) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL25264 | 0.77 | TDP1 (0.68) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451654-A | Addition polymerization catalyst | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-09-19 | — | — | US | disclosed |
| US-5387654-A | Hydroxy-peroxides and their uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0381135-B1 | Novel hydroxy-peroxides and their uses | ATOCHEM NORTH AMERICA (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5304649-A | Curing agent for unsaturated polyesters | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0381135-A2 | Novel hydroxy-peroxides and their uses | ATOCHEM NORTH AMERICA, INC. (US) | 1990-08-08 | — | — | EP | disclosed |