Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760802 | 1.00 | ACE (0.62) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL10907547 | 1.00 | ACE (0.62) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL7760836 | 1.00 | ACE (0.62) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL4656258 | 1.00 | ACE (0.62) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL4655446 | 1.00 | ACE (0.62) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL7426555 | 0.92 | ACE (0.53) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL7428034 | 0.89 | ACE (0.59) | ACERIPK1 | |
| SCHEMBL13979488 | 0.89 | ACE (0.59) | ACERIPK1 | |
| SCHEMBL13979490 | 0.82 | RIPK1 (0.48) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL11071769 | 0.81 | ACE (0.48) | ACEABCB11AGTR2PDE3ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079176-A1 | PROCESS FOR PREPARATION OF 3-[(1'-(ALKOXYCARBONYL)-3'-PHENYLPROPYL)AMINO]-2-OXO-[1]-BENZAZEPINE AND ITS DERIVATIVES | SCINOPHARM SINGAPORE PTE LTD (SG) | 2001-10-25 | — | — | WO | disclosed |