Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760802 | 1.00 | ACE (0.62) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL10907547 | 1.00 | ACE (0.62) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL7760836 | 1.00 | ACE (0.62) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL7756853 | 1.00 | ACE (0.62) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL4655446 | 1.00 | ACE (0.62) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL7426555 | 0.92 | ACE (0.53) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL7428034 | 0.89 | ACE (0.59) | ACERIPK1 | |
| SCHEMBL13979488 | 0.89 | ACE (0.59) | ACERIPK1 | |
| SCHEMBL13979490 | 0.82 | RIPK1 (0.48) | ACEABCB11AGTR2PDE3ATDP1 | |
| SCHEMBL11071769 | 0.81 | ACE (0.48) | ACEABCB11AGTR2PDE3ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430031-B1 | KINETIC RESOLUTION OF A INTERMEDIATE USEFUL IN THE PRODUCTION OF BENAZEPRIL AND ANALOGUES THEREOF | SCINOPHARM TAIWAN LTD (TW) | 2008-12-03 | — | — | EP | disclosed |
| EP-1430031-A4 | KINETIC RESOLUTION OF A INTERMEDIATE USEFUL IN THE PRODUCTION OF BENAZEPRIL AND ANALOGUES THEREOF | SCINOPHARM TAIWAN LTD (TW) | 2004-10-13 | — | — | EP | disclosed |
| EP-1430031-A2 | KINETIC RESOLUTION OF A INTERMEDIATE USEFUL IN THE PRODUCTION OF BENAZEPRIL AND ANALOGUES THEREOF | Scinopharm Taiwan, Ltd. (TW) | 2004-06-23 | — | — | EP | disclosed |
| US-20030055245-A1 | Kinetic resolution of a intermediate useful in the production of benazepril and analogues thereof | SCINOPHARM TAIWAN, LTD. | 2003-03-20 | — | — | US | disclosed |
| WO-2003003972-A2 | KINETIC RESOLUTION OF A INTERMEDIATE USEFUL IN THE PRODUCTION OF BENAZEPRIL AND ANALOGUES THEREOF | SCINOPHARM TAIWAN, LTD. (TW) | 2003-01-16 | — | — | WO | disclosed |
| WO-2001079176-A1 | PROCESS FOR PREPARATION OF 3-[(1'-(ALKOXYCARBONYL)-3'-PHENYLPROPYL)AMINO]-2-OXO-[1]-BENZAZEPINE AND ITS DERIVATIVES | SCINOPHARM SINGAPORE PTE LTD (SG) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055245-A1 | Kinetic resolution of a intermediate useful in the production of benazepril and analogues thereof | GABRE, GABRA4, GABRB1 | ACE 19/4885ABCB11 2047/4885AGTR2 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.