⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780041 | 0.75 | GABRP (0.31) | — | |
| SCHEMBL28019803 | 0.72 | — | — | |
| SCHEMBL8486435 | 0.70 | — | — | |
| SCHEMBL8528734 | 0.64 | — | — | |
| SCHEMBL11490268 | 0.64 | — | — | |
| SCHEMBL2467076 | 0.59 | — | — | |
| Bicarbonate SCHEMBL9715355 | 0.58 | — | — | |
| Azetidine SCHEMBL7551428 | 0.55 | — | — | |
| Piperazine SCHEMBL5875145 | 0.55 | HIF1A (0.55) | — | |
| Piperazine SCHEMBL3794325 | 0.55 | HIF1A (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084892-B2 | Preparation of optically active cis-1,3-dibenzyl-hexahydro-1H-furo(3,4-d)imidazole-2,4-dione and its intermediates | SUMITOMO CHEMICAL CO (JP) | 1996-10-23 | — | — | EP | claimed |
| EP-0084892-B1 | PREPARATION OF OPTICALLY ACTIVE CIS-1,3-DIBENZYL-HEXAHYDRO-1H-FURO(3,4-D)IMIDAZOLE-2,4-DIONE AND ITS INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-12-23 | — | — | EP | claimed |
| US-4544635-A | Preparation of optically active cis-1,3-dibenzyl-hexahydro-1H-furo[3,4-d]imidazole-2,4-dione and its intermediates | SUMITOMO CHEMICAL CO., LTD. (JP) | 1985-10-01 | — | — | US | claimed |
| US-4496739-A | Intermediates to optically active cis-1,3-dibenzyl-hexahydro-1H-furo[3,4-d]imidazole-2,4-dione | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-01-29 | — | — | US | claimed |
| EP-0084892-A2 | Preparation of optically active cis-1,3-dibenzyl-hexahydro-1H-furo(3,4-d)imidazole-2,4-dione and its intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-03 | — | — | EP | claimed |
| JP-58128386-A | — | — | None | — | — | JP | disclosed |
| JP-62239985-A | — | — | None | — | — | JP | disclosed |
| JP-62239998-A | — | — | None | — | — | JP | disclosed |
| JP-62239984-A | — | — | None | — | — | JP | disclosed |
| JP-58192886-A | — | — | None | — | — | JP | disclosed |
| EP-1081139-A3 | Preparation of an imidazolidinedicarboxylic acid | F. HOFFMANN-LA ROCHE AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| EP-1081139-A2 | Preparation of an imidazolidinedicarboxylic acid | F. HOFFMANN-LA ROCHE AG (CH) | 2001-03-07 | — | — | EP | disclosed |
| US-4544635-A | Preparation of optically active cis-1,3-dibenzyl-hexahydro-1H-furo[3,4-d]imidazole-2,4-dione and its intermediates | SUMITOMO CHEMICAL CO., LTD. (JP) | 1985-10-01 | — | — | US | disclosed |
| US-4544635-A | Preparation of optically active cis-1,3-dibenzyl-hexahydro-1H-furo[3,4-d]imidazole-2,4-dione and its intermediates | SUMITOMO CHEMICAL CO., LTD. (JP) | 1985-10-01 | — | — | US | disclosed |
| US-4496739-A | Intermediates to optically active cis-1,3-dibenzyl-hexahydro-1H-furo[3,4-d]imidazole-2,4-dione | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-01-29 | — | — | US | disclosed |
| US-4496739-A | Intermediates to optically active cis-1,3-dibenzyl-hexahydro-1H-furo[3,4-d]imidazole-2,4-dione | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-01-29 | — | — | US | disclosed |
| JP-S58192886-A | PREPARATION OF OPTICALLY ACTIVE LACTONE | SUMITOMO CHEM CO LTD | 1983-11-10 | — | — | JP | disclosed |
| EP-0084892-A2 | Preparation of optically active cis-1,3-dibenzyl-hexahydro-1H-furo(3,4-d)imidazole-2,4-dione and its intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-03 | — | — | EP | disclosed |
| EP-0084892-A2 | Preparation of optically active cis-1,3-dibenzyl-hexahydro-1H-furo(3,4-d)imidazole-2,4-dione and its intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-03 | — | — | EP | disclosed |
| JP-S58128386-A | PREPARATION OF OPTICAL ACTIVE LACTONE | SUMITOMO CHEM CO LTD | 1983-07-30 | — | — | JP | disclosed |