Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL3794325 | 0.95 | HIF1A (0.55) | — | |
| Piperazine SCHEMBL5875145 | 0.95 | HIF1A (0.55) | — | |
| Piperazine SCHEMBL2727552 | 0.91 | HIF1A (0.50) | — | |
| Pyrrolidine SCHEMBL712847 | 0.88 | — | — | |
| Azetidine SCHEMBL7551428 | 0.86 | — | — | |
| Piperidine SCHEMBL4577836 | 0.84 | ALDH1A1 (0.64) | — | |
| Piperidine SCHEMBL720107 | 0.84 | ALDH1A1 (0.64) | — | |
| Azepane SCHEMBL714889 | 0.84 | ALDH1A1 (0.64) | — | |
| Bicarbonate SCHEMBL16668464 | 0.84 | CXCR4 (0.64) | — | |
| Aziridine SCHEMBL30833516 | 0.84 | HIF1A (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118290-B1 | PROCESS FOR RECOVERING ETHYLENEAMINES FROM AQUEOUS SOLUTION OF ETHYLENEAMINE CARBONATES | Tosoh Corporation (JP) | 1988-07-27 | — | — | EP | claimed |
| EP-0118290-A1 | Process for recovering ethyleneamines from aqueous solution of ethyleneamine carbonates | Tosoh Corporation (JP) | 1984-09-12 | — | — | EP | claimed |
| JP-59161337-A | — | — | None | — | — | JP | disclosed |
| JP-59161338-A | — | — | None | — | — | JP | disclosed |
| JP-60126248-A | — | — | None | — | — | JP | disclosed |
| JP-60120842-A | — | — | None | — | — | JP | disclosed |
| US-20260007754-A1 | Conjugate Molecules | DIVERSE BIOTECH INC (US) | 2026-01-08 | — | — | US | disclosed |
| US-12121584-B2 | Conjugate molecules | DIVERSE BIOTECH, INC. (US) | 2024-10-22 | — | — | US | disclosed |
| CN-110997639-B | Process for preparing cyclic alkylene ureas | 诺力昂化学品国际有限公司 | 2024-03-12 | — | — | CN | disclosed |
| US-20240075149-A1 | Conjugate Molecules | DIVERSE BIOTECH, INC. | 2024-03-07 | — | — | US | disclosed |
| US-11919866-B2 | Process for preparing cyclic alkylene ureas | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2024-03-05 | — | — | US | disclosed |
| EP-0096571-B1 | PROCESS FOR RECOVERING ETHYLENEAMINES | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1986-09-03 | — | — | EP | disclosed |
| US-4582937-A | SOLVENT EXTRACTION USING ALICYCLIC KETONES OR ALDEHYDES | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1986-04-15 | — | — | US | disclosed |
| JP-S60126248-A | DECARBONATION OF AQUEOUS SOLUTION OF CARBONIC ACID SALT OF ETHYLENEAMINE COMPOUND | TOYO SODA MFG CO LTD | 1985-07-05 | — | — | JP | disclosed |
| JP-S60120842-A | PREPARATION OF ETHYLENEAMINES FROM ETHYLENEAMINE CARBONATES | TOYO SODA MFG CO LTD | 1985-06-28 | — | — | JP | disclosed |
| JP-S59161338-A | METHOD OF OBTAINING ETHYLENEAMINE FROM AQUEOUS SOLUTION OF ETHYLENEAMINE CARBONATE | TOYO SODA MFG CO LTD | 1984-09-12 | — | — | JP | disclosed |
| JP-S59161337-A | DECARBOXYLATION OF ETHYLENEAMINE CARBONATE | TOYO SODA MFG CO LTD | 1984-09-12 | — | — | JP | disclosed |
| EP-0118290-A1 | Process for recovering ethyleneamines from aqueous solution of ethyleneamine carbonates | Tosoh Corporation (JP) | 1984-09-12 | — | — | EP | disclosed |
| EP-0118290-A1 | Process for recovering ethyleneamines from aqueous solution of ethyleneamine carbonates | Tosoh Corporation (JP) | 1984-09-12 | — | — | EP | disclosed |
| EP-0096571-A2 | Process for recovering ethyleneamines | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1983-12-21 | — | — | EP | disclosed |