Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757127 | 1.00 | PTGS2 (0.35) | PTGS2PTGS1KDM1ARCOR1HTR1A | |
| SCHEMBL7756330 | 0.87 | PTGS2 (0.33) | PTGS2PTGS1KDM1ARCOR1HTR1A | |
| SCHEMBL7756333 | 0.87 | PTGS2 (0.33) | PTGS2PTGS1KDM1ARCOR1HTR1A | |
| SCHEMBL7757557 | 0.84 | CYP11B2 (0.36) | KDM1ADRD2HTR2A | |
| SCHEMBL7757563 | 0.84 | CYP11B2 (0.36) | KDM1ADRD2HTR2A | |
| SCHEMBL7752952 | 0.83 | SPHK1 (0.38) | PTGS2PTGS1 | |
| SCHEMBL7752954 | 0.83 | SPHK1 (0.38) | PTGS2PTGS1 | |
| SCHEMBL7759925 | 0.83 | CYP2C9 (0.41) | KDM1ARCOR1 | |
| SCHEMBL8416897 | 0.83 | CYP2C9 (0.41) | KDM1ARCOR1 | |
| SCHEMBL7759927 | 0.83 | CYP2C9 (0.41) | KDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696591-B1 | Process for preparing silacyclohexane-based liquid crystal compounds | SHINETSU CHEMICAL CO (JP) | 2001-03-14 | — | — | EP | disclosed |
| EP-0673942-B1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | SHINETSU CHEMICAL CO (JP) | 2000-11-08 | — | — | EP | disclosed |
| EP-0650969-B1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5659059-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5641431-A | Silacyclohexanone compound and a method of preparing a silacyclohexane-type liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| US-5514824-A | Process for preparing silacyclohexane-base liquid crystal compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0696591-A1 | Process for preparing silacyclohexane-based liquid crystal compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0673942-A1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-27 | — | — | EP | disclosed |
| EP-0650969-A1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-05-03 | — | — | EP | disclosed |