SCHEMBL7757137

SCHEMBL7757137

CCC(C)C(F)(C(N)=O)C1CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 3/20 0.32
DPP4 P27487 3/20 0.32
DPP7 Q9UHL4 2/20 0.32
DPP9 Q86TI2 1/20 0.31
LIPA P38571 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7762287 0.93 EPHX1 (0.33) DPP8DPP4DPP7
SCHEMBL7760192 0.93 DPP8 (0.31) DPP8DPP4DPP7
SCHEMBL7763716 0.80 ALOX5 (0.32) LIPA
SCHEMBL7761975 0.73 ALOX5 (0.31)
SCHEMBL7762241 0.73 EPHX1 (0.33)
SCHEMBL7761229 0.73 ALOX5 (0.35) DPP8DPP4DPP7DPP9
SCHEMBL7760175 0.71 MAPT (0.33) DPP8DPP4DPP7
SCHEMBL7760140 0.71 CA1 (0.31)
SCHEMBL7761232 0.70 MAPT (0.36) DPP8DPP4DPP7LIPA
SCHEMBL7763689 0.69 ALOX5 (0.33) DPP8DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1089962-A1 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY AMERICAN BIOGENETIC SCIENCES, INC. (US) 2001-04-11 EP disclosed
WO-1999067199-A1 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY AMERICAN BIOGENETIC SCIENCES INC. (US) 1999-12-29 WO disclosed