SCHEMBL7760192

SCHEMBL7760192

CCC(C)C(F)(C(N)=O)C1CCC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 2/20 0.31
DPP7 Q9UHL4 2/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7762287 0.97 EPHX1 (0.33) DPP8DPP7DPP4
SCHEMBL7757137 0.93 DPP8 (0.32) DPP8DPP7DPP4
SCHEMBL7761975 0.82 ALOX5 (0.31)
SCHEMBL7762241 0.78 EPHX1 (0.33)
SCHEMBL7763716 0.74 ALOX5 (0.32)
SCHEMBL7763689 0.73 ALOX5 (0.33) DPP8DPP7
SCHEMBL7761229 0.70 ALOX5 (0.35) DPP8DPP7DPP4
SCHEMBL7760175 0.69 MAPT (0.33) DPP8DPP7DPP4
SCHEMBL7760140 0.69 CA1 (0.31)
SCHEMBL7761147 0.68 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1089962-A1 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY AMERICAN BIOGENETIC SCIENCES, INC. (US) 2001-04-11 EP disclosed
WO-1999067199-A1 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY AMERICAN BIOGENETIC SCIENCES INC. (US) 1999-12-29 WO disclosed