Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.30 |
| ▸ | CES2 | O00748 | 2/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000384 | 0.85 | CES2 (0.44) | FAAHCES2CES1 | |
| SCHEMBL5936843 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TSHRHTT | |
| SCHEMBL7082748 | 0.80 | CES2 (0.37) | ALDH1A1FAAHCES2CES1 | |
| SCHEMBL28298521 | 0.79 | TDP1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL14968474 | 0.76 | MEN1 (0.35) | ALDH1A1FAAHCES2CES1 | |
| SCHEMBL14968473 | 0.76 | MEN1 (0.35) | ALDH1A1FAAHCES2CES1 | |
| SCHEMBL5936825 | 0.75 | ALDH1A1 (0.31) | ALDH1A1TSHRFAAHCES2 | |
| SCHEMBL28248190 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TSHRHTT | |
| SCHEMBL9652201 | 0.74 | — | — | |
| SCHEMBL11813029 | 0.73 | TSHR (0.38) | ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089962-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1089960-A1 | ALPHA-FLUORO ALKYNOIC ACIDS WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| US-6184401-B1 | ANTICONVULSANTS,-EPILEPTIC AGENTS; COMPARABLE TO VALPROIC ACID IN THEIR PREVENTION OF SEIZURES BUT HAVE REDUCED TERATOGENIC POTENTIAL, LONGER DURATION OF ACTION AND REDUCED SIDE EFFECTS | AMERICAN BIOGENETIC SCIENCES | 2001-02-06 | — | — | US | disclosed |
| WO-1999067195-A1 | ALPHA-FLUORO ALKYNOIC ACIDS WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| WO-1999067199-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |