Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | ATF4 | P18848 | 3/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757209 | 1.00 | PARP10 (0.38) | PARP10PARP15TRPV4ATF4GSK3B | |
| SCHEMBL7761363 | 0.90 | PARP10 (0.40) | PARP10PARP15SLC6A2SLC6A4HTR3A | |
| SCHEMBL7761368 | 0.90 | PARP10 (0.40) | PARP10PARP15SLC6A2SLC6A4HTR3A | |
| SCHEMBL7760352 | 0.88 | PARP10 (0.41) | PARP10PARP15SLC6A2SLC6A4HTR3A | |
| SCHEMBL7760350 | 0.88 | PARP10 (0.41) | PARP10PARP15SLC6A2SLC6A4HTR3A | |
| SCHEMBL7760360 | 0.87 | TP53 (0.39) | PARP10PARP15SLC6A2SLC6A4HTR3A | |
| SCHEMBL7760358 | 0.87 | TP53 (0.39) | PARP10PARP15SLC6A2SLC6A4HTR3A | |
| SCHEMBL7760411 | 0.84 | PARP10 (0.34) | PARP10PARP15FFAR4SCN9A | |
| SCHEMBL7760416 | 0.84 | PARP10 (0.34) | PARP10PARP15FFAR4SCN9A | |
| SCHEMBL7757353 | 0.84 | TRPV4 (0.38) | PARP10PARP15TRPV4ATF4GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714899-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-04-18 | — | — | EP | disclosed |
| US-5641430-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0714899-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |