Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760358 | 1.00 | TP53 (0.39) | TP53GAAMCL1KMT2ASMN1; SMN2 | |
| SCHEMBL7757209 | 0.87 | PARP10 (0.38) | SLC6A2SLC6A4HTR3AKCNH2PARP15 | |
| SCHEMBL7757213 | 0.87 | PARP10 (0.38) | SLC6A2SLC6A4HTR3AKCNH2PARP15 | |
| SCHEMBL7761399 | 0.84 | MCL1 (0.39) | TP53GAAMCL1KMT2ASMN1; SMN2 | |
| SCHEMBL7761395 | 0.84 | MCL1 (0.39) | TP53GAAMCL1KMT2ASMN1; SMN2 | |
| SCHEMBL7761404 | 0.84 | MCL1 (0.39) | TP53GAAMCL1KMT2ASMN1; SMN2 | |
| SCHEMBL7763803 | 0.83 | TDP1 (0.40) | KMT2AMEN1ALDH1A1KCNH2 | |
| SCHEMBL7763797 | 0.83 | TDP1 (0.40) | KMT2AMEN1ALDH1A1KCNH2 | |
| SCHEMBL7761363 | 0.81 | PARP10 (0.40) | SLC6A2SLC6A4HTR3AKCNH2PARP15 | |
| SCHEMBL7761368 | 0.81 | PARP10 (0.40) | SLC6A2SLC6A4HTR3AKCNH2PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714899-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-04-18 | — | — | EP | disclosed |
| US-5641430-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0714899-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |