Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761234 | 0.85 | POLB (0.35) | HRH3SIGMAR1 | |
| SCHEMBL7765244 | 0.82 | KCNH2 (0.33) | KCNH2HRH3 | |
| SCHEMBL7765247 | 0.82 | KCNH2 (0.33) | KCNH2HRH3 | |
| SCHEMBL8977238 | 0.80 | HRH3 (0.38) | KCNH2HRH3GRM2SIGMAR1CHRM3 | |
| SCHEMBL7763766 | 0.80 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL7763781 | 0.79 | CHRM3 (0.33) | CHRM3CHRM2CHRM1 | |
| SCHEMBL7760259 | 0.78 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL7758795 | 0.75 | TSHR (0.33) | KCNH2HRH3CHRM3CHRM2CHRM4 | |
| SCHEMBL7751108 | 0.73 | ALDH1A1 (0.37) | KCNH2HRH3GRM2CHRM3CHRM2 | |
| SCHEMBL7767656 | 0.73 | HRH3 (0.30) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714899-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-04-18 | — | — | EP | disclosed |
| US-5641430-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0714899-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |