Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751108 | 0.91 | ALDH1A1 (0.37) | HRH3CYP1A2KCNH2CHRM2CHRM5 | |
| SCHEMBL7757304 | 0.80 | KCNH2 (0.36) | HRH3CYP1A2KCNH2CHRM2CHRM4 | |
| SCHEMBL8455093 | 0.76 | CYP1A2 (0.39) | HRH3CYP1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL8455094 | 0.76 | CYP1A2 (0.39) | HRH3CYP1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL7758021 | 0.73 | ACHE (0.31) | MEN1KMT2ACYP2C9 | |
| SCHEMBL7765247 | 0.73 | KCNH2 (0.33) | HRH3KCNH2 | |
| SCHEMBL7765244 | 0.73 | KCNH2 (0.33) | HRH3KCNH2 | |
| SCHEMBL9156291 | 0.72 | HRH3 (0.52) | HRH3KCNH2SIGMAR1 | |
| SCHEMBL9346249 | 0.72 | HRH3 (0.56) | HRH3KCNH2SIGMAR1 | |
| SCHEMBL9346253 | 0.72 | HRH3 (0.56) | HRH3KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |