Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | ATF4 | P18848 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757347 | 1.00 | TRPV4 (0.38) | TRPV4PARP10PARP15ATF4SCN9A | |
| SCHEMBL7757353 | 1.00 | TRPV4 (0.38) | TRPV4PARP10PARP15ATF4SCN9A | |
| SCHEMBL7761412 | 0.90 | PARP10 (0.40) | TRPV4PARP10PARP15SCN9AFFAR4 | |
| SCHEMBL7761418 | 0.90 | PARP10 (0.40) | TRPV4PARP10PARP15SCN9AFFAR4 | |
| SCHEMBL7761415 | 0.90 | PARP10 (0.40) | TRPV4PARP10PARP15SCN9AFFAR4 | |
| SCHEMBL7761399 | 0.87 | MCL1 (0.39) | PARP10PARP15PDE2A | |
| SCHEMBL7761404 | 0.87 | MCL1 (0.39) | PARP10PARP15PDE2A | |
| SCHEMBL7761395 | 0.87 | MCL1 (0.39) | PARP10PARP15PDE2A | |
| SCHEMBL7763800 | 0.84 | PARP10 (0.41) | TRPV4PARP10PARP15ATF4SCN9A | |
| SCHEMBL7757246 | 0.84 | PARP10 (0.34) | PARP10PARP15SCN9APDE2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714899-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-04-18 | — | — | EP | disclosed |
| US-5641430-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0714899-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |