Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761404 | 1.00 | MCL1 (0.39) | MCL1KMT2ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL7761399 | 1.00 | MCL1 (0.39) | MCL1KMT2ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL7757353 | 0.87 | TRPV4 (0.38) | PDE2APARP15PARP10 | |
| SCHEMBL7757350 | 0.87 | TRPV4 (0.38) | PDE2APARP15PARP10 | |
| SCHEMBL7757347 | 0.87 | TRPV4 (0.38) | PDE2APARP15PARP10 | |
| SCHEMBL7760358 | 0.84 | TP53 (0.39) | MCL1KMT2ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL7760360 | 0.84 | TP53 (0.39) | MCL1KMT2ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL7761418 | 0.81 | PARP10 (0.40) | PARP15PARP10 | |
| SCHEMBL7761415 | 0.81 | PARP10 (0.40) | PARP15PARP10 | |
| SCHEMBL7761412 | 0.81 | PARP10 (0.40) | PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714899-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-04-18 | — | — | EP | disclosed |
| US-5641430-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0714899-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |