SCHEMBL7757396

SCHEMBL7757396

CC(C)(CCO)OC(=O)c1cccc(O[O])c1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.34
PDK2 Q15119 1/20 0.34
PDK3 Q15120 1/20 0.34
PDK4 Q16654 1/20 0.34
JAK2 O60674 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
ELANE P08246 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TAS1R2 Q8TE23 1/20 0.31
PTGS2 P35354 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753324 0.82 CYP3A4 (0.33) PDK1PDK2PDK3PDK4JAK2
SCHEMBL12559789 0.69 ELANE (0.41) ESR1ESR2ELANECYP1A2CYP3A4
SCHEMBL9340184 0.69 TSHR (0.59) JAK2ESR1PTGS2CYP1A2CYP2C9
SCHEMBL6582605 0.68 SLC7A5 (0.37) PDK1PDK2PDK3PDK4JAK2
SCHEMBL4640131 0.67 ADRB2 (0.38) ESR1ESR2ADRB2ADRB1ADRB3
SCHEMBL7756830 0.67 UTS2R (0.35) ADRB2ADRB1ADRB3
SCHEMBL31099217 0.66 ALDH1A1 (0.52) L3MBTL1CYP3A4
SCHEMBL9103077 0.66 GRM6 (0.38) ESR1ESR2ELANENPSR1
SCHEMBL11985721 0.66 IRAK4 (0.55) ELANENPSR1KDM4E
SCHEMBL7755987 0.66 ALDH1A1 (0.31) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850927-B1 Novel oxalic acid peroxide compositions and their uses ATOFINA CHEM INC (US) 2001-03-14 EP disclosed
US-5866712-A POLYMERIZATION AND CURING CATALYSTS ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-02-02 US disclosed
EP-0850927-A1 Novel oxalic acid peroxide compositions and uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed
US-5451654-A Addition polymerization catalyst ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-09-19 US disclosed
US-5387654-A Hydroxy-peroxides and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-02-07 US disclosed
EP-0381135-B1 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA (US) 1994-06-01 EP disclosed
US-5304649-A Curing agent for unsaturated polyesters ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-19 US disclosed
EP-0381135-A2 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA, INC. (US) 1990-08-08 EP disclosed