Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757400 | 1.00 | DRD2 (0.39) | DRD2DRD4PARP15PARP10PARP2 | |
| SCHEMBL7757416 | 1.00 | DRD2 (0.39) | DRD2DRD4PARP15PARP10PARP2 | |
| SCHEMBL9813502 | 0.82 | ACACB (0.48) | DRD2DRD4SIGMAR1 | |
| SCHEMBL8398649 | 0.80 | CYP2C9 (0.46) | DRD2 | |
| SCHEMBL8432734 | 0.80 | MAOB (0.44) | — | |
| SCHEMBL8398660 | 0.80 | CYP2C9 (0.46) | DRD2 | |
| SCHEMBL8398656 | 0.80 | CYP2C9 (0.46) | DRD2 | |
| SCHEMBL8977329 | 0.80 | MAOB (0.44) | — | |
| SCHEMBL8432737 | 0.80 | MAOB (0.44) | — | |
| SCHEMBL24180195 | 0.78 | PARP15 (0.55) | DRD2DRD4PARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714899-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-04-18 | — | — | EP | disclosed |
| US-5641430-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0714899-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |