Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665006 | 0.98 | LMNA (0.52) | LMNAGAAKDM4EMAPTTHRB | |
| SCHEMBL29113077 | 0.95 | LMNA (0.50) | LMNAGAAKDM4EMAPTTHRB | |
| SCHEMBL28413733 | 0.79 | CA1 (0.52) | MAPTACHEALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5655838 | 0.78 | LMNA (0.56) | LMNAGAAKDM4EMAPTTHRB | |
| SCHEMBL1401005 | 0.76 | LMNA (0.54) | LMNAGAAKDM4EMAPTTHRB | |
| SCHEMBL2000856 | 0.74 | LMNA (0.52) | LMNAGAAKDM4EMAPTTHRB | |
| SCHEMBL11485692 | 0.74 | LMNA (0.52) | LMNAGAAKDM4EMAPTTHRB | |
| SCHEMBL1401003 | 0.74 | LMNA (0.58) | LMNAGAAKDM4EMAPTTHRB | |
| SCHEMBL11485695 | 0.74 | LMNA (0.52) | LMNAGAAKDM4EMAPTTHRB | |
| SCHEMBL28673744 | 0.74 | ESR2 (0.46) | LMNAGAAKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798313-B1 | OLEFIN POLYMERIZATION CATALYST | ASAHI CHEMICAL IND (JP) | 2001-03-21 | — | — | EP | disclosed |