SCHEMBL2000856

SCHEMBL2000856

Cc1ccc(OC(=S)Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
GAA P10253 2/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
THRB P10828 1/20 0.47
ACHE P22303 2/20 0.44
ALDH1A1 P00352 3/20 0.41
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KMT2A Q03164 5/20 0.38
MEN1 O00255 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
TEAD4 Q15561 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10754710 0.81 CA1 (0.52) LMNAMAPTKDM4EACHEALDH1A1
SCHEMBL5655838 0.80 LMNA (0.56) LMNAGAAMAPTKDM4ETHRB
SCHEMBL1401005 0.78 LMNA (0.54) LMNAGAAMAPTKDM4ETHRB
SCHEMBL1462548 0.78 LMNA (0.40) LMNAMAPTALDH1A1NPC1HPGD
SCHEMBL10626679 0.77 ACHE (0.41) LMNAGAAMAPTKDM4ETHRB
SCHEMBL11485695 0.76 LMNA (0.52) LMNAGAAMAPTKDM4ETHRB
SCHEMBL742569 0.76 MAOA (0.41) GAAALDH1A1NPC1RAB9AKMT2A
SCHEMBL1401003 0.76 LMNA (0.58) LMNAGAAMAPTKDM4ETHRB
SCHEMBL11485692 0.76 LMNA (0.52) LMNAGAAMAPTKDM4ETHRB
SCHEMBL652260 0.76 LMNA (0.64) LMNAGAAMAPTACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2026-04-16 US claimed
US-12416066-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2025-09-16 US claimed
US-20250092487-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2025-03-20 US claimed
EP-4461833-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS Jetti Resources, LLC (US) 2024-11-13 EP claimed
US-20240336991-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-10-10 US claimed
US-12049681-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-07-30 US claimed
EP-3283661-B1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES LLC (US) 2024-06-05 EP claimed
US-20240167121-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-05-23 US claimed
US-11859263-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-01-02 US claimed
WO-2022245731-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2022-11-24 WO claimed
EP-3233803-B1 PROCESS FOR THE PREPARATION OF A DIARYLTHIOHYDANTOIN COMPOUND ARAGON PHARMACEUTICALS INC (US) 2019-01-30 EP claimed
EP-3233803-A2 PROCESS FOR THE PREPARATION OF A DIARYLTHIOHYDANTOIN COMPOUND Aragon Pharmaceuticals, Inc. (US) 2017-10-25 EP claimed
US-9688655-B2 Process for the preparation of a diarylthiohydantoin compound JANSSEN PHARMACEUTICA NV (BE) 2017-06-27 US claimed
WO-2016100652-A2 PROCESS FOR THE PREPARATION OF A DIARYLTHIOHYDANTOIN COMPOUND ARAGON PHARMACEUTICALS, INC. (US) 2016-06-23 WO claimed
US-20160176844-A1 PROCESSES FOR THE PREPARATION OF A DIARYLTHIOHYDANTOIN COMPOUND JANSSEN PHARMACEUTICA NV (BE) 2016-06-23 US claimed
US-20160176845-A1 PROCESS FOR THE PREPARATION OF A DIARYLTHIOHYDANTOIN COMPOUND JANSSEN PHARMACEUTICA NV (BE) 2016-06-23 US claimed
EP-0280929-B1 MONO- AND DIEPOXIDE DERIVATIVES OF 23-DEOXY-LL-F28249 COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1993-09-15 EP claimed
US-4551545-A Process of preparing alkyl cis chrysanthemates ROUSSEL UCLAF (FR) 1985-11-05 US claimed
EP-4214343-B1 EXTRACTING BASE METALS USING A WETTING AGENT AND A THIOCARBONYL FUNCTIONAL GROUP REAGENT JETTI RESOURCES LLC (US) 2026-05-06 EP disclosed
US-4328335-A PARASITICIDES, CULTURE PRODUCT OF STREPTOMYCES REACTED WITH A THIOCARBONYL HALIDE MERCK & CO., INC. (US) 1982-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160176845-A1 PROCESS FOR THE PREPARATION OF A DIARYLTHIOHYDANTOIN COMPOUND BPHL, CYP4X1, KLK3 LMNA 1758/4885GAA 3605/4885MAPT 3227/4885
US-20160176844-A1 PROCESSES FOR THE PREPARATION OF A DIARYLTHIOHYDANTOIN COMPOUND BPHL, CYP4X1, KLK3 LMNA 1559/4885GAA 3426/4885MAPT 3359/4885
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS TST, FECH, SLC6A12 LMNA 4643/4885GAA 3949/4885MAPT 3485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.