SCHEMBL7757572

SCHEMBL7757572

ON1c2ccccc2Cc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AADAT Q8N5Z0 2/20 0.47
GOT1 P17174 1/20 0.47
KYAT1 Q16773 1/20 0.47
KYAT3 Q6YP21 1/20 0.47
NOTUM Q6P988 1/20 0.44
RNASEH1 O60930 1/20 0.42
HPGD P15428 1/20 0.42
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41
TUBB6 Q9BUF5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13826481 0.84 MEN1 (0.48) AADATGOT1KYAT1KYAT3NOTUM
SCHEMBL29836002 0.81 RNASEH1 (0.60) AADATGOT1KYAT1KYAT3NOTUM
SCHEMBL3195836 0.81 RNASEH1 (0.60) AADATGOT1KYAT1KYAT3NOTUM
SCHEMBL21082763 0.76 TLR9 (0.43) AADATGOT1KYAT1KYAT3HPGD
SCHEMBL25138589 0.74 HPGD (0.42) NOTUMHPGDTSHRDRD1DRD2
SCHEMBL20776999 0.74 NOTUM (0.44) NOTUMHPGDTSHRDRD1DRD2
SCHEMBL29351597 0.74 MAOA (0.52) NOTUMHPGDTSHRDRD1DRD2
SCHEMBL975897 0.74 MAOA (0.52) NOTUMHPGDTSHRDRD1DRD2
SCHEMBL12320654 0.74 HPGD (0.42) NOTUMHPGDTSHRDRD1DRD2
SCHEMBL28642675 0.74 HPGD (0.42) NOTUMHPGDTSHRDRD1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120289884-A1 Fused Ring Diarylamino Photosensitizers for Phototherapy MALLINCKRODT LLC (US) 2012-11-15 US disclosed
US-20120289884-A1 Fused Ring Diarylamino Photosensitizers for Phototherapy MALLINCKRODT LLC (US) 2012-11-15 US disclosed
CN-1085218-C Olefin polymerization catalyst ASAHI CHEMICAL IND (JP) 2002-05-22 CN disclosed
US-6214954-B1 HOMO OR COPOLYMERIZING AN OLEFIN WITH POLYMERIZATION CATALYST COMPRISING A TRANSITION METAL COMPOUND, CYCLOPENTADIENYL RING CONTAINING LIGAND AND A CHELATING LIGAND, PRODUCES POLYMER WITH NARROW MOLECULAR WEIGHT DISTRIBUTION AND UNIFORMITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-04-10 US disclosed
EP-0798313-B1 OLEFIN POLYMERIZATION CATALYST ASAHI CHEMICAL IND (JP) 2001-03-21 EP disclosed
EP-0798313-A1 OLEFIN POLYMERIZATION CATALYST Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1997-10-01 EP disclosed