Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.47 |
| ▸ | RXRG | P48443 | 7/20 | 0.47 |
| ▸ | RXRB | P28702 | 7/20 | 0.47 |
| ▸ | RARB | P10826 | 5/20 | 0.47 |
| ▸ | RARG | P13631 | 5/20 | 0.47 |
| ▸ | RARA | P10276 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 6/20 | 0.44 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757695 | 1.00 | RXRA (0.47) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7754539 | 0.90 | RXRA (0.56) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7754546 | 0.90 | RXRA (0.56) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7789472 | 0.82 | RXRA (0.54) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7789470 | 0.82 | RXRA (0.54) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7755074 | 0.81 | RXRA (0.47) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7755067 | 0.81 | RXRA (0.47) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7757722 | 0.80 | RXRA (0.51) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7757729 | 0.80 | RXRA (0.51) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7756532 | 0.78 | RXRA (0.51) | RXRARXRGRXRBRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077919-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | claimed |
| WO-1999058486-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | claimed |